Skookum into Chad Michael Murry

MyHeritage: Family tree - Genealogy - Celeb

Profile

MEDICAL FACTS:
My gallbladder died-emergency removal
Gallstones-My risk=11.1%=1.58x7.0%Typ.
Hypertriglyceridemia [started decade ago], yet my data says I have typical odds:
rs964184-CC
Diagnosed as bipolar for almost two decades and meds made my high stress career liveable, 
but my data says I have reduced odds:
rs4948418- CC


True Believers think:
1.Large segment sizes are passed intact and are proof we have detectable cousins. 
2.Segments are tested and can be detected in 23andMe raw data. 
3.They are doing a public service when they stalk others to proselytize and/or intimidate 
them with harassment. 
4.I care about their opinions even when Iam mostly revolted by them. manipulative and 
abusive stalking of me on every post, including those where I originated the topic. 
5.Consider it their duty to derail the posts and topics of with whom they disagree with 
personal attacks and irrelevant off topic provocations.
Invisible Pink Unicorn in its Natural Habitat
http://www.facebook.com/photo.php?fbid=10150538693581457
With the Hopes that our World is built on they were utterly out of touch,
They denied that the Moon was Stilton; they denied she was even Dutch;
They denied that Wishes were Horses; they denied that a Pig had Wings;
So we worshipped the Gods of the Market Who promised these beautiful things.
Rudyard Kipling-The Gods of the Copybook Headings
Do not try to convince the True Believers.

http://www.law.cornell.edu/uscode/usc_sec_42_00001320---d006-.html

http://www.fbi.gov/atlanta/press-releases/2011/fake-doctor-sentenced-for-health-care-fraud-and-criminal-hipaa-violations

This is my list to remind myself not to respond to their provoking remarks:
thetick:
fauxdk:
AndreaBadger:
GeeBee of Bavaria:
Geneadict:
altai volk:
Maureen Higgins Markov:
Tanaquil:
Glenn N.:
MMaddi:

DNFTT

Family Surnames

Beauchamp, Bird, Blythe, Carruthers, Childress, Ehart, Fielding, Gowder, Hall, Headen, 
Hobson, Hueston, Little, Massey, McConnell, McDonald, Montgomery, Moore, Norwood, 
Reinholds, Reynolds, Rucker, Scharf, Shurvington, Woods, Work

Family Locations

Oregon, Washington, Kentucky, Arkansas, Texas, Georgia, South Carolina, North Carolina, 
Virginia, Scotland, Kent, England, Ireland, Germany, France, Ireland, Isle of Sky,

Geographic Facts: 

Father-orphaned in Denver;lived in Nebraska. Mother born Arkansas;ancestry in KY, GA, SC, 
NC,&Virginia. 

My maternal lineage is, starting with my mother:

Noda Moore-AR
Lillian Rucker-AR
Susan Willie Caldoni Saffroni Little-AR
Susan Childress-AR
Susan Elvina Childress-GA
Sarah Massey-NC
Sarah Work-SC
Margaret [Unknown]-VA
This is a reader's digest version of my maternal lineage:
http://webspace.webring.com/people/tu/um_910/MOORE.HT

Diagnosed Type II Diabetes though my data say I have average risk:

rs7903146-CT
Type 2 Diabetes:My Risk=25.3%=.98x25.7% Typical risk
I have T2D/Type II Diabetes and one maternal aunt who has it. It did not start until my 
mid-50s. I retired from 26 years of working in corrections, which kept me physically 
active. 
I have hypertriglerides and we have them under control, which may be why my 
mother/aunts were affected with late onset AD.  Diet does not seem to work. Meds do not 
seem to work. I may have to exercise more. 

All my med. history is documented with my health insurance company and my offspring are 

few, so I am willing to participate in any research. My full genome sequence for my mtDNA 
is already public with the NCIB and I am an open book on my medical history.


I am diagnosed and treated for being bipolar. The True Believers who have not yet 
admitted and gotten treatment are a pain.

MY DNA MADE PUBLIC:

I am J1c3d yDNA and H3 mtDNA per FTDNA.These are my places for data on my DNA:

http://www.snpedia.com/index.php/User:JohnLloydScharf
http://www.facebook.com/media/set/?set=a.427524841456.204572.637766456
http://www.facebook.com/groups/HaplogroupJ1/

Haplogroup J1c3d-P58+ M267+ L147.1+ M369- M368- M367- L65.2- L222.2- L174-

http://testing-johnlloydscharf.blogspot.com/2011/12/my-mtdna.html
http://en.wikipedia.org/wiki/User:JohnLloydScharf/J1draft
http://www.facebook.com/groups/213733318644557/

Haplogroup - H3

http://en.wikipedia.org/wiki/User:JohnLloydScharf/Haplogroup_H3_(mtDNA)
http://www.ncbi.nlm.nih.gov/nuccore/JN020360
HVR1 differences from CRS:16519C 
HVR2 differences from CRS:263G,315.1C 
CR differences from CRS:750G,1438G,4769G,6776C,714­8C, 8860G,15326G,15519C

My mtDNA Fasta File
http://testing-johnlloydscharf.blogspot.com/2011/12/my-mtdna.html
My mtDNA Data Processed
http://testing-johnlloydscharf.blogspot.com/2011/12/my-ydna.html
X STRS:
http://testing-johnlloydscharf.blogspot.com/2011/12/my-x-str-results.html
Autosomal STRS: 
http://testing-johnlloydscharf.blogspot.com/2011/12/my-autosomal-str-results.html
Notes On My 23andMe Raw Data
http://testing-johnlloydscharf.blogspot.com/2011/12/notes-on-my-23andme-raw-data.html
My mtDNA haplogroup/haplotype: 
http://www.facebook.com/photo.php?fbid=10150258318196457 
My mtDNA disease profile: 
http://www.facebook.com/photo.php?fbid=10150437948586457 
My yDNA haplotype 
http://www.facebook.com/photo.php?fbid=10150258318201457 
My yDNA haplogroup 
http://www.facebook.com/photo.php?fbid=10150258318206457 
My yDNA STRs 
http://www.facebook.com/photo.php?fbid=10150256641206457 
http://www.facebook.com/photo.php?fbid=10150304085646457 
My autosomal STRs 
http://www.facebook.com/photo.php?fbid=10150266430616457 
My X-STRs 
http://www.facebook.com/photo.php?fbid=10150256652721457
https://www.23andme.com/you/community/guidelines/
23andMe kit number:
GED M211533
GED M083415
GED Kit Number: F125649
FTDNA Kit Number: 125649A
My raw data at:
http://opensnp.org/users/141
Process it at one of the following. 
http://www.math.mun.ca/~dapike/FF23utils/
http://esquilax.stanford.edu/
Database for Autism:
http://autismkb.cbi.pku.edu.cn/
List of SNP-trait associations

http://snp.ims.u-tokyo.ac.jp/cgi-bin/list_gwas.cgi

On FTDNA, my shared cM runs from 20.77cM to 66.02cM and includes 138 individuals.

23andM for the same range of 20.77cm to 66.02cM in RF, it includes 41 individuals.
About Me
Tiffany at 23andMe Customer Service (Tiffany B.) wrote:Dec 20, 2011
(6 hours ago)
John,
We have suspended your Community posting privileges effective immediately. Your recent posts are in violation of the Terms of Service agreement as well as our Community Guidelines. See https://www.23andme.com/about/tos/and https://www.23andme.com/you/community/guidelines/ 
Please note that you still have the ability to send and receive messages and invitations. Also, this revocation does not affect access to your data or account. Should we receive reports from other users that you are abusing the messaging system, that privilege will also be terminated immediately without notice.
Let me know if you have any questions.
Sincerely,
Tiffany

Atrial Fibrillation

CHROMOSOME ONE(1)

KCNN3 153080977 rs13376333 C or T CC
MAF/MinorAlleleCount: T=0.221/483
P=6.3×10−12
Common Variants in KCNN3 are Associated with Lone Atrial Fibrillation
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/

AGT 228912417 rs699 A or G AA
MAF/MinorAlleleCount: A=0.339/741
FBAT-P =.044
We observed significant association between tagging-SNP rs699 (M235T), located in exon 2 of the AGT gene, and AF. The AA genotype of rs699 increased the risk of AF by 70% (95% confidence interval, 1.01-2.85; P = .044) under a recessive model (AA vs AG + GG).
http://www.sciencedirect.com/science/article/pii/S0022073609005378

CHROMOSOME TWO(2)

C2orf86 63607779 rs2421954 C or T TT
MAF/MinorAlleleCount: C=0.379/829
FBAT-P=1.51E-04 LOC51057
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/


CHROMOSOME THREE(3)

intergenic 110400929 rs1163397 C or T TT=AA
MAF/MinorAlleleCount: C=0.388/850
FBAT-P=1.78E-04
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

CD200 113538529 rs10511311 A or T AA
MAF/MinorAlleleCount: T=0.238/520
P= 4.5 × 10-5
AF,rs10511311 in CD200, p = 4.5 × 10 -5 ;
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

CHROMOSOME FOUR(4)

USO1 76924038 rs324735 A or T TT
MAF/MinorAlleleCount: A=0.292/638
FBAT-P=9.98E-05
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

intergenic 111929618 rs2200733 C or T CC
MAF/MinorAlleleCount: T=0.270/591
Single nucleotide polymorphism (SNP) rs2200733 was associated with AF in all four cohorts, with odds ratios (ORs) ranging from 1.37 in Rotterdam [95% confidence interval (CI) 1.18–1.59; P = 3.1 × 10−5] to 2.52 in AFNet (95% CI 2.22–2.8; P=1.8 × 10−49).
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663727/table/EHN578TB2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2663727/
http://www.nature.com/nature/journal/v448/n7151/abs/nature06007.html


intergenic 111937516 rs6843082 A or G GG
MAF/MinorAlleleCount:G=0.408/892
P=2.5×10−28
The most significant SNP at this locus was rs6843082 (OR 2.03, 95% CI, 1.79–2.30; P=2.5×10−28,PITX2
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/

intergenic 111940210 rs10033464 G or T TT
MAF/MinorAlleleCount:T=0.163/357
A meta-analysis of the current and prior AF studies revealed an OR of 1.90 (95% CI 1.60–2.26; P = 3.3 × 10−13) for rs2200733 and of 1.36 (95% CI 1.26–1.47; P = 6.7 × 10−15) for rs10033464.
http://eurheartj.oxfordjournals.org/content/30/7/813.full
http://www.nature.com/nature/journal/v448/n7151/abs/nature06007.html
http://www.snpedia.com/index.php/Rs10033464(T;T)

CHROMOSOME ELEVEN(11)

intergenic 97372875 rs4590838 C or T CC
MAF/MinorAlleleCount: T=0.187/409
GEE-P=4.03E-05
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387

CNTN5 98998383 rs10501920 C or G CC
MAF/MinorAlleleCount: G=0.149/325
GEE-P=9.40E-06
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/


CHROMOSOME TWELVE(12)

rs1427828
intergenic 88286630 rs1427828 C or G CC=GG
MAF/MinorAlleleCount: C=0.499/1091
FBAT-P=4.58E-05 DUSP6
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

CHROMOSOME FOURTEEN(14)

RAD51L1 67747245 rs1298340 C or G GG
MAF/MinorAlleleCount: C=0.126/276
FBAT-P=7.40E-05
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

RAD51L1 67769347 rs1314913 C or T CC
MAF/MinorAlleleCount: T=0.108/236
FBAT-P=5.53E-05
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/


CHROMOSOME SIXTEEN(16)

ZFHX3 71586661 rs7193343 C or T CC
MAF/MinorAlleleCount:T=0.311/68
P = 1.4x10-10
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke-A variant in the ZFHX3 gene on chromosome 16q22, rs7193343-T, associated significantly with AF (odds ratio OR = 1.21, P = 1.4  10-10).
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
http://www.nature.com/ng/journal/v41/n8/full/ng.417.html
Atrial Natriuretic Peptide Frameshift Mutation in Familial Atrial Fibrillation
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518320/

CHROMOSOME TWENTY(20)


intergenic 45858983 rs13038095 G or T GG
MAF/MinorAlleleCount:T=0.103/226
P=1.1×10−8  SULF2
A third SNP, rs13038095 on chromosome 20q13, also exceeded genome-wide significance (OR 1.61, 95% CI 1.37–1.91, p=1.1×10−8)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/table/T2/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387/
http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0023215/full

===========================================================

For genotype-phenotype association analyses, we assumed an additive-allele model of inheritance and we conducted association tests using regression models with generalized estimating equations (GEE), as well as family-based association testing using FBAT.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995607/

Am I 31.5% Pharoah????

See:
http://jama.ama-assn.org/content/303/7/638.full

Notes On My 23andMe Raw Data

Runs of Homozygosity (ROHs)

At 200: 35 ROH 
At 195: 39 ROH 
At 190: 41 ROH 
At 180: 51 ROH 
At 170: 65 ROH 
At 160: 73 ROH 
At 150: 94 ROH 
At 140: 119 ROH 
At 130: 147 ROH 
At 120: 197 ROH 
At 110: 265 ROH 
At 100: 353 ROH 
At 90: 473 ROH 
At 80: 620 ROH 
At 70: 820 ROH 
At 60: 1127 ROH 
At 50: 1617 ROH 
At 40: 2356 ROH 
At 30: 3590 ROH 
At 20: 5963 ROH 
At 10: 12483 ROH 
At 2: 83753 ROH 
Total autosomal (Chr 1-22): 29.258 % (272188 of 930296 SNPs) are Heterozygous (this tally excludes 3 heterozygous SNPs that were treated as homozygous). 

Heterozygous Sequences

Heterozygous Sequences of length at least 20=3
Heterozygous Sequences of length at least 18=6
Heterozygous Sequences of length at least 17=14
Heterozygous Sequences of length at least 16=18
Heterozygous Sequences of length at least 15=29
Heterozygous Sequences of length at least 14=44
Heterozygous Sequences of length at least 13=81
Heterozygous Sequences of length at least 12=130
Heterozygous Sequences of length at least 11=221
Heterozygous Sequences of length at least 10=424
Heterozygous Sequences of length at least 09=706
Heterozygous Sequences of length at least 08=1242
Heterozygous Sequences of length at least 07=2291
Heterozygous Sequences of length at least 06=4208
Heterozygous Sequences of length at least 05=8222
Heterozygous Sequences of length at least 04=16061
Heterozygous Sequences of length at least 03=31605
Heterozygous Sequences of length at least 02=64378
29.259%(272191 of 930296 SNPs)are Heterozygous (this tally excludes NoCalls)

My yDNA

HAPLOGROUP INFO

Your Haplogroup	Tests
J1c3d	P58+ M267+ L147.1+ M369- M368- M367- L65.2- L222.2- L174-

PANEL 1 (1-12)

Locus	1	2	3	4	5	6	7	8	9	10	11	12
DYS#	393	390	19*	391	385a	385b	426	388	439	389-1	392	389-2
Alleles	12	23	14	10	12	17	11	16	12	13	11	30

PANEL 2 (13-25)

Locus	13	14	15	16	17	18	19	20	21	22	23	24	25
DYS#	458	459a	459b	455	454	447	437	448	449	464a**	464b**	464c**	464d**
Alleles	17	8	9	11	11	26	14	20	25	12	14	16	17

PANEL 3 (26-37)

Locus	26	27	28	29	30	31	32	33	34	35	36	37
DYS#	460	GATA H4	YCA II a	YCA II b	456	607	576	570	CDY a	CDY b	442	438
Alleles	11	10	22	22	15	14	18	19	34	34	12	10

PANEL 4 (38 - 47)

Locus	38	39	40	41	42	43	44	45	46	47
DYS#	531	578	395S1a	395S1b	590	537	641	472	406S1	511
Alleles	11	8	15	16	8	11	10	8	11	9

PANEL 4 (48 - 60)

Locus	48	49	50	51	52	53	54	55	56	57	58	59	60
DYS#	425	413a	413b	557	594	436	490	534	450	444	481	520	446
Alleles	12	21	22	18	10	12	12	15	8	12	24	21	14

PANEL 4 (61 - 67)

Locus	61	62	63	64	65	66	67
DYS#	617	568	487	572	640	492	565
Alleles	12	11	14	12	12	12	11

PANEL 5 (68 - 75)

Locus	68	69	70	71	72	73	74	75
DYS#	710	485	632	495	540	714	716	717
Alleles	33	14	8	15	12	26	27	20

PANEL 5 (76 - 85)

Locus	76	77	78	79	80	81	82	83	84	85
DYS#	505	556	549	589	522	494	533	636	575	638
Alleles	13	11	12	11	12	9	11	11	10	11

PANEL 5 (86 - 93)

Locus	86	87	88	89	90	91	92	93
DYS#	462	452	445	GATA A10	463	441	GGAAT 1B07	525
Alleles	11	31	7	13	22	14	11	10

PANEL 5 (94 - 102)

Locus	94	95	96	97	98	99	100	101	102
DYS#	712	593	650	532	715	504	513	561	552
Alleles	20	15	20	10	22	15	11	15	24

PANEL 5 (103 - 111)

Locus	103	104	105	106	107	108	109	110	111
DYS#	726	635	587	643	497	510	434	461	435
Alleles	12	21	18	9	15	17	9	11	11

*Also known as DYS 394

**On 5/19/2003, these values were adjusted down by 1 point because of a change in Lab nomenclature.

***A value of “0” for any marker indicates that the lab reported a null value or no result for this marker. All cases of this nature are retested multiple times by the lab to confirm their accuracy. Mutations causing null values are infrequent, but are passed on to offspring just like other mutations, so related male lineages such as a father and son would likely share any null values.

Advanced Markers

Results from the Advanced order page.

Understanding your results.

Y-STR DNA PANEL - KITTLER
DYS#	DYS385a/b (K)
ALLELES	12-17

Y-STR DNA-FP PANEL 2
DYS#	DYS463	DYS643
ALLELES	22	9

Y-STR DNA-FP PANEL 3
DYS#	DYS461	DYS462	DYS635	DYS726
ALLELES	11	11	21	12

Y-STR DNA-FP PANEL 4
DYS#	DYS426	DYS434	DYS435	DYS441	DYS445	DYS452	DYS454	DYS455	DYS485	DYS495	DYS714	DYS716	DYS717	Y-GATA-A10	Y-GGAAT-1B07
ALLELES	11	9	11	14	7	31	11	11	14	15	26	27	20	13	11

Y-STR DNA-FP PANEL 5 PALINDROMIC PACK
DYS#	DYF371X	DYF385	DYF397	DYF399X	DYF401	DYF408	DYF411	DYS413	DYS464X	DYS724	DYS725
ALLELES	10c-12t-13c-15c	10-10	14-14-14-14	19c-24t-24.1t	14-14	188-188-9-9	12-13	21-22	12g-14g-16g-17g	34-34	28-29-32-32

Y-STR DNA-FP PANEL 7
DYS#	DYS436	DYS444	DYS446
ALLELES	12	12	14

Y-STR DNA-FP PANEL 9
DYS#	DYS494	DYS505	DYS522	DYS533	DYS549	DYS556	DYS575	DYS589	DYS636	DYS638
ALLELES	9	13	12	11	12	11	10	11	11	11

Y-STR PANEL 1
DYS#	DYS710
ALLELES	33.2

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